Gene: LOC107986556

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: RIPK1

Alternate names for this Gene: AIEFL|IMD57|RIP|RIP-1|RIP1

Gene Summary: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.

Gene is located in Chromosome: 6

Location in Chromosome : 6p25.2

Description of this Gene: receptor interacting serine/threonine kinase 1

Type of Gene: protein-coding

rs17548308 in LOC107986556;RIPK1 gene and High density lipoprotein measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs374657927 in LOC107986556;RIPK1 gene and Primary immune deficiency disorder PMID 30591564 2019 Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases.

rs17548308 in LOC107986556;RIPK1 gene and Serum HDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.