Gene: LRRC63
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Type of Gene:
Gene: LOC107984578
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Gene: LCP1
Alternate names for this Gene: CP64|HEL-S-37|L-PLASTIN|LC64P|LPL|PLS2
Gene Summary: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
Gene is located in Chromosome: 13
Location in Chromosome : 13q14.13
Description of this Gene: lymphocyte cytosolic protein 1
Type of Gene: protein-coding