Gene: MED12L

Alternate names for this Gene: NIZIDS|NOPAR|TNRC11L|TRALP|TRALPUSH

Gene Summary: The protein encoded by this gene is part of the Mediator complex, which is involved in transcriptional coactivation of nearly all RNA polymerase II-dependent genes. The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery.

Gene is located in Chromosome: 3

Location in Chromosome : 3q25.1

Description of this Gene: mediator complex subunit 12L

Type of Gene: protein-coding

rs11708767 in MED12L gene and Alzheimer's Disease PMID 30514930 2018 Genetic data and cognitively defined late-onset Alzheimer's disease subgroups.

rs16863355 in MED12L gene and Triglycerides measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.