Gene: MIR708

Alternate names for this Gene: MIRN708|hsa-mir-708

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 11

Location in Chromosome : 11q14.1

Description of this Gene: microRNA 708

Type of Gene: ncRNA

Gene: TENM4

Alternate names for this Gene: Doc4|ETM5|ODZ4|TEN4|TNM4|Ten-M4|ten-4

Gene Summary: The protein encoded by this gene plays a role in establishing proper neuronal connectivity during development. Defects in this gene have been associated with hereditary essential tremor-5.

Gene is located in Chromosome: 11

Location in Chromosome : 11q14.1

Description of this Gene: teneurin transmembrane protein 4

Type of Gene: protein-coding