Gene: MRC1

Alternate names for this Gene: CD206|CLEC13D|CLEC13DL|MMR|MRC1L1|bA541I19.1|hMR

Gene Summary: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.

Gene is located in Chromosome: 10

Location in Chromosome : 10p12.33

Description of this Gene: mannose receptor C-type 1

Type of Gene: protein-coding

rs2477664 in MRC1 gene and Aspartate aminotransferase measurement PMID 20139978 2010 Genome-wide association study of hematological and biochemical traits in a Japanese population.

rs149410244 in MRC1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.