Gene: MYO16
Alternate names for this Gene: MYAP3|MYR8|Myo16b|NYAP3|PPP1R107
Gene Summary: This gene encodes an unconventional myosin protein. The encoded protein has been proposed to act as a serine/threonine phosphatase-1 targeting or regulatory subunit. Studies in a rat cell line suggest that this protein may regulate cell cycle progression. A variant within this gene may be associated with susceptibility to schizophrenia and elevated expression of this gene has been observed in the frontal cortex of human schizophrenia patients.
Gene is located in Chromosome: 13
Location in Chromosome : 13q33.3
Description of this Gene: myosin XVI
Type of Gene: protein-coding
rs9583269 in
MYO16 gene and
Adenocarcinoma of large intestine
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9284241 in
MYO16 gene and
Adolescent idiopathic scoliosis
PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
rs150813880 in
MYO16 gene and
Alzheimer's Disease
PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.
PMID 23535033 2014 Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
rs7984522 in
MYO16 gene and
Blood Pressure
PMID 22763476 2012 Genome-wide linkage and association scans for pulse pressure in Chinese twins.
rs9583269 in
MYO16 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 1
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9583269 in
MYO16 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 10
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9583269 in
MYO16 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 12
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9583269 in
MYO16 gene and
COLORECTAL CANCER, SUSCEPTIBILITY TO, 3
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9583269 in
MYO16 gene and
Colorectal Carcinoma
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9583269 in
MYO16 gene and
Colorectal Neoplasms
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9521159 in
MYO16 gene and
Depressed bipolar I disorder
PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.
rs9521010 in
MYO16 gene and
Finding of Mean Corpuscular Hemoglobin
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
rs9583269 in
MYO16 gene and
Malignant neoplasm of large intestine
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9583269 in
MYO16 gene and
Malignant tumor of colon
PMID 29228715 2017 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.
rs9521017 in
MYO16 gene and
Mean Corpuscular Volume (result)
PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
rs9521011 in
MYO16 gene and
Red Blood Cell Count measurement
PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.
PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.
rs9284241 in
MYO16 gene and
SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3
PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.
rs78553789 in
MYO16 gene and
Smoking
PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
rs78553789 in
MYO16 gene and
Smoking Behaviors
PMID 26053186 2015 Mercapturic Acids Derived from the Toxicants Acrolein and Crotonaldehyde in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.
rs78667595 in
MYO16 gene and
mathematical ability
PMID 30038396 2018 Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.