Gene: NIN

Alternate names for this Gene: SCKL7

Gene Summary: This gene encodes one of the proteins important for centrosomal function. This protein is important for positioning and anchoring the microtubules minus-ends in epithelial cells. Localization of this protein to the centrosome requires three leucine zippers in the central coiled-coil domain. Multiple alternatively spliced transcript variants that encode different isoforms have been reported.

Gene is located in Chromosome: 14

Location in Chromosome : 14q22.1

Description of this Gene: ninein

Type of Gene: protein-coding

rs61755581 in NIN gene and Breast Carcinoma PMID 30787463 2019 Genome-wide association study of germline variants and breast cancer-specific mortality.

rs72681698 in NIN gene and Diastolic blood pressure PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.

rs8012283 in NIN gene and Lupus Erythematosus, Systemic PMID 24925725 2014 Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

rs8012283 in NIN gene and Lupus Nephritis PMID 24925725 2014 Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

rs146291102 in NIN gene and Platelet mean volume determination (procedure) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs72681698 in NIN gene and Systolic Pressure PMID 30578418 2019 Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.