Gene: NTN1
Alternate names for this Gene: MRMV4|NTN1L
Gene Summary: Netrin is included in a family of laminin-related secreted proteins. The function of this gene has not yet been defined; however, netrin is thought to be involved in axon guidance and cell migration during development. Mutations and loss of expression of netrin suggest that variation in netrin may be involved in cancer development.
Gene is located in Chromosome: 17
Location in Chromosome : 17p13.1
Description of this Gene: netrin 1
Type of Gene: protein-coding
rs10468483 in
NTN1 gene and
Blood Protein Measurement
PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.
PMID 29875488 2018 Genomic atlas of the human plasma proteome.
rs12944377 in
NTN1 gene and
Cleft Palate
PMID 28054174 2017 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.
PMID 25775280 2015 Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate.
rs12944377 in
NTN1 gene and
Cleft upper lip
PMID 28054174 2017 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.
PMID 25775280 2015 Genome-wide association study identifies a new susceptibility locus for cleft lip with or without a cleft palate.
PMID 20436469 2010 A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4.
PMID 22863734 2012 Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.
rs12944377 in
NTN1 gene and
Oral cleft
PMID 28054174 2017 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.