Gene: OSBPL7

Alternate names for this Gene: ORP7

Gene Summary: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: oxysterol binding protein like 7

Type of Gene: protein-coding

rs16948401 in OSBPL7 gene and Body Fat Distribution PMID 30664634 2019 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.

rs9911983 in OSBPL7 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.