Gene: PHRF1

Alternate names for this Gene: PPP1R125|RNF221

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11p15.5

Description of this Gene: PHD and ring finger domains 1

Type of Gene: protein-coding

rs4963128 in PHRF1 gene and Lupus Erythematosus, Systemic PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PMID 19838195 2009 A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus.

rs4963128 in PHRF1 gene and Multiple Sclerosis PMID 22190364 2011 Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci.

rs936469 in PHRF1 gene and Systemic Scleroderma PMID 23740937 2013 A systemic sclerosis and systemic lupus erythematosus pan-meta-GWAS reveals new shared susceptibility loci.