Gene: POU2F3
Alternate names for this Gene: Epoc-1|OCT-11|OCT11|OTF-11|PLA-1|PLA1|Skn-1a
Gene Summary: This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type-specific differentiation pathways. The encoded protein is primarily expressed in the epidermis, and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein, and aberrant promoter methylation of this gene may play a role in cervical cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene is located in Chromosome: 11
Location in Chromosome : 11q23.3
Description of this Gene: POU class 2 homeobox 3
Type of Gene: protein-coding
Gene: LOC105369531
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