Gene: PPP1R42

Alternate names for this Gene: LRRC67|TLLR|TLRR|dtr

Gene Summary: The protein encoded by this gene can interact with gamma-tubulin and PP1 phosphatase, a regulator of centrosome separation. The encoded protein is a positive regulator of PP1 phosphatase and thus plays a role in the control of centrosome integrity.

Gene is located in Chromosome: 8

Location in Chromosome : 8q13.1

Description of this Gene: protein phosphatase 1 regulatory subunit 42

Type of Gene: protein-coding

rs182838111 in PPP1R42 gene and Alzheimer's Disease PMID 26830138 2016 Family-based association analyses of imputed genotypes reveal genome-wide significant association of Alzheimer's disease with OSBPL6, PTPRG, and PDCL3.