Gene: PSMD6

Alternate names for this Gene: Rpn7|S10|SGA-113M|p42A|p44S10

Gene Summary: This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants

Gene is located in Chromosome: 3

Location in Chromosome : 3p14.1

Description of this Gene: proteasome 26S subunit, non-ATPase 6

Type of Gene: protein-coding

rs3816157 in PSMD6 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.

PMID 26818947 2016 Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.

rs66473811 in PSMD6 gene and Glomerular Filtration Rate PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.