Gene: RIPK1

Alternate names for this Gene: AIEFL|IMD57|RIP|RIP-1|RIP1

Gene Summary: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.

Gene is located in Chromosome: 6

Location in Chromosome : 6p25.2

Description of this Gene: receptor interacting serine/threonine kinase 1

Type of Gene: protein-coding

rs17513478 in RIPK1 gene and High density lipoprotein measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs17513478 in RIPK1 gene and Low density lipoprotein cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs1561772403 in RIPK1 gene and Primary immune deficiency disorder PMID 30591564 2019 Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases.

rs17513478 in RIPK1 gene and Serum HDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs17513478 in RIPK1 gene and Serum LDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs17513478 in RIPK1 gene and Serum total cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.