Gene: SETBP1
Alternate names for this Gene: MRD29|SEB
Gene Summary: This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene is located in Chromosome: 18
Location in Chromosome : 18q12.3
Description of this Gene: SET binding protein 1
Type of Gene: protein-coding