Gene: SLC24A4

Alternate names for this Gene: AI2A5|NCKX4|SHEP6|SLC24A2

Gene Summary: This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 14

Location in Chromosome : 14q32.12

Description of this Gene: solute carrier family 24 member 4

Type of Gene: protein-coding

rs587777536 in SLC24A4 gene and AMELOGENESIS IMPERFECTA, HYPOMATURATION TYPE, IIA5 PMID 24621671 2014 STIM1 and SLC24A4 Are Critical for Enamel Maturation.

PMID 23375655 2013 Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta.

rs10498633 in SLC24A4 gene and Alzheimer's Disease PMID 31473137 2019 Genome-wide association analysis of dementia and its clinical endophenotypes reveal novel loci associated with Alzheimer's disease and three causality networks: The GR@ACE project.

PMID 24162737 2013 Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

PMID 25778476 2016 A novel Alzheimer disease locus located near the gene encoding tau protein.

PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.

PMID 29777097 2018 GWAS on family history of Alzheimer's disease.

rs11160059 in SLC24A4 gene and Blood Pressure PMID 21378095 2011 Association of genetic variation with systolic and diastolic blood pressure among African Americans: the Candidate Gene Association Resource study.

rs78598185 in SLC24A4 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs12883151 in SLC24A4 gene and Hair Color PMID 30531825 2018 Genome-wide study of hair colour in UK Biobank explains most of the SNP heritability.

PMID 26184321 2015 Heritability and Genome-Wide Association Studies for Hair Color in a Dutch Twin Family Based Sample.