Gene: SLC6A4
Alternate names for this Gene: 5-HTT|5-HTTLPR|5HTT|HTT|OCD1|SERT|SERT1|hSERT
Gene Summary: This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.
Gene is located in Chromosome: 17
Location in Chromosome : 17q11.2
Description of this Gene: solute carrier family 6 member 4
Type of Gene: protein-coding