Gene: SPIC

Alternate names for this Gene: SPI-C

Gene Summary: The protein encoded by this gene regulates the development of red pulp macrophages, which are necessary for iron homeostasis and the recycling of red blood cells.

Gene is located in Chromosome: 12

Location in Chromosome : 12q23.2

Description of this Gene: Spi-C transcription factor

Type of Gene: protein-coding

rs2373459 in SPIC gene and High density lipoprotein measurement PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

rs17041439 in SPIC gene and Lymphocyte Count measurement PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs17041439 in SPIC gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.