Gene: STAM

Alternate names for this Gene: STAM-1|STAM1

Gene Summary: This gene encodes a member of the signal-transducing adaptor molecule family. These proteins mediate downstream signaling of cytokine receptors and also play a role in ER to Golgi trafficking by interacting with the coat protein II complex. The encoded protein also associates with hepatocyte growth factor-regulated substrate to form the endosomal sorting complex required for transport-0 (ESCRT-0), which sorts ubiquitinated membrane proteins to the ESCRT-1 complex for lysosomal degradation. Alternatively spliced transcript variants have been observed for this gene.

Gene is located in Chromosome: 10

Location in Chromosome : 10p12.33

Description of this Gene: signal transducing adaptor molecule

Type of Gene: protein-coding