Gene: STMN2

Alternate names for this Gene: SCG10|SCGN10

Gene Summary: This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

Gene is located in Chromosome: 8

Location in Chromosome : 8q21.13

Description of this Gene: stathmin 2

Type of Gene: protein-coding

rs2979715 in STMN2 gene and Degenerative polyarthritis PMID 22763110 2012 Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study.

rs113889867 in STMN2 gene and Major Depressive Disorder PMID 25897834 2015 The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.

rs113889867 in STMN2 gene and response to SSRI PMID 25897834 2015 The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.