Gene: TACC3
Alternate names for this Gene: ERIC-1|ERIC1|Tacc4|maskin
Gene Summary: This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells.
Gene is located in Chromosome: 4
Location in Chromosome : 4p16.3
Description of this Gene: transforming acidic coiled-coil containing protein 3
Type of Gene: protein-coding
rs798766 in
TACC3 gene and
Carcinoma of bladder
PMID 20972438 2010 A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
PMID 20348956 2010 The T allele of rs798766 on 4p16.3 was found to associate with UBC (odds ratio = 1.24, P = 9.9 x 10(-12)). rs798766 is located in an intron of TACC3, 70 kb from FGFR3, which often harbors activating somatic mutations in low-grade, noninvasive UBC.
rs28499138 in
TACC3 gene and
Lean body mass
PMID 30593698 2019 Genomics of body fat percentage may contribute to sex bias in anorexia nervosa.
rs798766 in
TACC3 gene and
Malignant neoplasm of urinary bladder
PMID 20348956 2010 The T allele of rs798766 on 4p16.3 was found to associate with UBC (odds ratio = 1.24, P = 9.9 x 10(-12)). rs798766 is located in an intron of TACC3, 70 kb from FGFR3, which often harbors activating somatic mutations in low-grade, noninvasive UBC.
PMID 20972438 2010 A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.