Condition: Malignant neoplasm of urinary bladder
rs10094872 in
CASC11 gene and
Malignant neoplasm of urinary bladder
PMID 24861552 2014 Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.
PMID 18794855 2008 No association was observed between UBC and the four 8q24 variants previously associated with prostate, colorectal and breast cancers, nor did rs9642880 associate with any of these three cancers.
PMID 20348956 2010 A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
PMID 20972438 2010 A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
rs4510656 in
CDKAL1 gene and
Malignant neoplasm of urinary bladder
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs401681 in
CLPTM1L gene and
Malignant neoplasm of urinary bladder
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
PMID 20972438 2010 A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
rs121913479 in
FGFR3 gene and
Malignant neoplasm of urinary bladder
PMID 10471491 1999 Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas.
PMID 11314002 2001 Loss of heterozygosity at 4p16.3 and mutation of FGFR3 in transitional cell carcinoma.
rs4813953 in
LINC02871 gene and
Malignant neoplasm of urinary bladder
PMID 24861552 2014 Genome-wide association study yields variants at 20p12.2 that associate with urinary bladder cancer.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs10775480 in
LOC105372093;SLC14A1 gene and
Malignant neoplasm of urinary bladder
PMID 21824976 2011 A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs907611 in
LSP1 gene and
Malignant neoplasm of urinary bladder
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs10936599 in
MYNN gene and
Malignant neoplasm of urinary bladder
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs5003154 in
PAG1 gene and
Malignant neoplasm of urinary bladder
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs2294008 in
PSCA;JRK gene and
Malignant neoplasm of urinary bladder
PMID 19648920 2009 Our data identify rs2294008 as a new bladder cancer susceptibility locus.
PMID 20972438 2010 A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
rs17674580 in
SLC14A1;LOC105372093 gene and
Malignant neoplasm of urinary bladder
PMID 21750109 2011 It is speculated that rs17674580, or other sequence variants in LD with it, indirectly modifies UBC risk by affecting urine production.
PMID 21824976 2011 A genome-wide association study of bladder cancer identifies a new susceptibility locus within SLC14A1, a urea transporter gene on chromosome 18q12.3.
rs798766 in
TACC3 gene and
Malignant neoplasm of urinary bladder
PMID 20348956 2010 The T allele of rs798766 on 4p16.3 was found to associate with UBC (odds ratio = 1.24, P = 9.9 x 10(-12)). rs798766 is located in an intron of TACC3, 70 kb from FGFR3, which often harbors activating somatic mutations in low-grade, noninvasive UBC.
PMID 20972438 2010 A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.
rs11892031 in
UGT1A10;UGT1A8 gene and
Malignant neoplasm of urinary bladder
PMID 20972438 2010 In a combined analysis, we identified three new regions associated with bladder cancer on chromosomes 22q13.1, 19q12 and 2q37.1: rs1014971, (P = 8 × 10⁻¹²) maps to a non-genic region of chromosome 22q13.1, rs8102137 (P = 2 × 10⁻¹¹) on 19q12 maps to CCNE1 and rs11892031 (P = 1 × 10⁻⁷) maps to the UGT1A cluster on 2q37.1.
PMID 24163127 2014 Genome-wide association study identifies multiple loci associated with bladder cancer risk.