Gene: TAS2R38

Alternate names for this Gene: PTC|T2R38|T2R61|THIOT

Gene Summary: This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant).

Gene is located in Chromosome: 7

Location in Chromosome : 7q34

Description of this Gene: taste 2 receptor member 38

Type of Gene: protein-coding

Gene: MGAM

Alternate names for this Gene: MG|MGA

Gene Summary: This gene encodes maltase-glucoamylase, which is a brush border membrane enzyme that plays a role in the final steps of digestion of starch. The protein has two catalytic sites identical to those of sucrase-isomaltase, but the proteins are only 59% homologous. Both are members of glycosyl hydrolase family 31, which has a variety of substrate specificities.

Gene is located in Chromosome: 7

Location in Chromosome : 7q34

Description of this Gene: maltase-glucoamylase

Type of Gene: protein-coding