Gene: TBX15

Alternate names for this Gene: TBX14

Gene Summary: This gene belongs to the T-box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T-box DNA-binding domain. Mutations in this gene are associated with Cousin syndrome.

Gene is located in Chromosome: 1

Location in Chromosome : 1p12

Description of this Gene: T-box transcription factor 15

Type of Gene: protein-coding

rs111668293 in TBX15 gene and Alopecia PMID 28196072 2017 Genetic prediction of male pattern baldness.

rs111668293 in TBX15 gene and Alopecia, Androgenetic, 1 PMID 29146897 2017 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

rs111668293 in TBX15 gene and Alopecia, Androgenetic, 2 PMID 29146897 2017 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

rs111668293 in TBX15 gene and Alopecia, Androgenetic, 3 PMID 29146897 2017 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

rs111668293 in TBX15 gene and Alopecia, Male Pattern PMID 29146897 2017 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

rs111668293 in TBX15 gene and Androgenetic Alopecia PMID 29146897 2017 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

rs2645289 in TBX15 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

rs9659323 in TBX15 gene and Body mass index PMID 25673413 2015 Genetic studies of body mass index yield new insights for obesity biology.

PMID 30108127 2018 A Large Multiethnic Genome-Wide Association Study of Adult Body Mass Index Identifies Novel Loci.

PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

rs2645288 in TBX15 gene and Breast size PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs984225 in TBX15 gene and Hirsutism PMID 29895819 2018 Excessive hairiness signals' top SNPs were also eQTLs for TBX15 (rs984225; P = 1.6 × 10<sup>-8</sup>), BCL2 (rs7226979; P = 7.3 × 10<sup>-11</sup>), and GCC2 and LIMS1 (rs6542772; P = 2.2 × 10<sup>-9</sup>).

rs111668293 in TBX15 gene and Other alopecia PMID 29146897 2017 GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.

rs10923712 in TBX15 gene and Physical Activity Measurement PMID 28448500 2017 Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.

rs10923712 in TBX15 gene and Smoking PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

rs10923712 in TBX15 gene and Smoking Behaviors PMID 28443625 2017 Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

rs10923712 in TBX15 gene and Waist-Hip Ratio PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 20935629 2010 Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.