Gene: THBD
Alternate names for this Gene: AHUS6|BDCA-3|BDCA3|CD141|THPH12|THRM|TM
Gene Summary: The protein encoded by this intronless gene is an endothelial-specific type I membrane receptor that binds thrombin. This binding results in the activation of protein C, which degrades clotting factors Va and VIIIa and reduces the amount of thrombin generated. Mutations in this gene are a cause of thromboembolic disease, also known as inherited thrombophilia.
Gene is located in Chromosome: 20
Location in Chromosome : 20p11.21
Description of this Gene: thrombomodulin
Type of Gene: protein-coding