Gene: TSPAN3

Alternate names for this Gene: TM4-A|TM4SF8|TSPAN-3

Gene Summary: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Multiple alternative transcripts encoding different isoforms have been described.

Gene is located in Chromosome: 15

Location in Chromosome : 15q24.3

Description of this Gene: tetraspanin 3

Type of Gene: protein-coding

rs377247337 in TSPAN3 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 30718926 2019 Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.