Gene: TSPOAP1-AS1

Alternate names for this Gene: BZRAP1-AS1

Gene Summary:

Gene is located in Chromosome: 17

Location in Chromosome : 17q22

Description of this Gene: TSPOAP1, SUPT4H1 and RNF43 antisense RNA 1

Type of Gene: ncRNA

Gene: MIR142

Alternate names for this Gene: MIRN142|mir-142

Gene Summary: microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop.

Gene is located in Chromosome: 17

Location in Chromosome : 17q22

Description of this Gene: microRNA 142

Type of Gene: ncRNA

rs2632516 in TSPOAP1-AS1;MIR142 gene and Alzheimer's Disease PMID 28183528 2017 Transethnic genome-wide scan identifies novel Alzheimer's disease loci.

PMID 30617256 2019 Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer's disease risk.

rs2632516 in TSPOAP1-AS1;MIR142 gene and Monocyte count procedure PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs2632516 in TSPOAP1-AS1;MIR142 gene and Monocyte count result PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.