Gene: WDR12

Alternate names for this Gene: YTM1

Gene Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein is highly similar to the mouse WD repeat domain 12 protein at the amino acid level. The protein encoded by this gene is a component of a nucleolar protein complex that affects maturation of the large ribosomal subunit.

Gene is located in Chromosome: 2

Location in Chromosome : 2q33.2

Description of this Gene: WD repeat domain 12

Type of Gene: protein-coding

Gene: CARF

Alternate names for this Gene: ALS2CR8|NYD-SP24

Gene Summary:

Gene is located in Chromosome: 2

Location in Chromosome : 2q33.2

Description of this Gene: calcium responsive transcription factor

Type of Gene: protein-coding

rs149268645 in WDR12;CARF gene and Bipolar Disorder PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

rs140244541 in WDR12;CARF gene and Low density lipoprotein cholesterol measurement PMID 25961943 2015 The impact of low-frequency and rare variants on lipid levels.

rs149268645 in WDR12;CARF gene and Major Depressive Disorder PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

rs138556413 in WDR12;CARF gene and Migraine Disorders PMID 27322543 2016 Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

rs17406900 in WDR12;CARF gene and Pseudocholinesterase Measurement PMID 21862451 2011 GWAS of butyrylcholinesterase activity identifies four novel loci, independent effects within BCHE and secondary associations with metabolic risk factors.

rs149268645 in WDR12;CARF gene and Schizophrenia PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.

rs149268645 in WDR12;CARF gene and Suicide attempt PMID 31164008 2019 GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores.