Gene: ZC3H12C

Alternate names for this Gene: MCPIP3

Gene Summary:

Gene is located in Chromosome: 11

Location in Chromosome : 11q22.3

Description of this Gene: zinc finger CCCH-type containing 12C

Type of Gene: protein-coding

Gene: RDX

Alternate names for this Gene: DFNB24

Gene Summary: Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 11

Location in Chromosome : 11q22.3

Description of this Gene: radixin

Type of Gene: protein-coding

rs10789752 in ZC3H12C;RDX gene and High density lipoprotein measurement PMID 29507422 2018 A large electronic-health-record-based genome-wide study of serum lipids.

PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.

PMID 30275531 2018 Genetics of blood lipids among ~300,000 multi-ethnic participants of the Million Veteran Program.

PMID 29083408 2017 Exome-wide association study of plasma lipids in >300,000 individuals.

rs661171 in ZC3H12C;RDX gene and Low density lipoprotein cholesterol measurement PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.

rs661171 in ZC3H12C;RDX gene and Parathyroid hormone measurement PMID 30134803 2018 Genome-wide meta-analysis identifies novel loci associated with parathyroid hormone level.

rs661171 in ZC3H12C;RDX gene and Serum total cholesterol measurement PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.

rs661171 in ZC3H12C;RDX gene and Triglycerides measurement PMID 30289880 2018 Heritability informed power optimization (HIPO) leads to enhanced detection of genetic associations across multiple traits.