Variant: rs1057519747 

    present in Gene: TP53
    present in Chromosome: 17
    Position on Chromosome: 7675094
    Alleles of this Variant: A/C;G;T

rs1057519747 in TP53 gene and Adenocarcinoma of lung (disorder) PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Adenocarcinoma of pancreas PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Adrenocortical carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Brain Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Brain Stem Glioma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Colorectal Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Cutaneous Melanoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Esophageal carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Gastric Adenocarcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Leukemia, Myelocytic, Acute PMID 24381225 2014 Haploinsufficiency of del(5q) genes, Egr1 and Apc, cooperate with Tp53 loss to induce acute myeloid leukemia in mice.

PMID 24487413 2014 Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients.

PMID 24641375 2014 Prognostic significance of TP53 mutations and single nucleotide polymorphisms in acute myeloid leukemia: a case series and literature review.

rs1057519747 in TP53 gene and Liver carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Malignant Uterine Corpus Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Mammary Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Neoplastic Syndromes, Hereditary PMID 20593220 2011 MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation.

PMID 18555592 2008 Presence of dominant negative mutation of TP53 is a risk of early recurrence in oral cancer.

PMID 24744791 2014 Patterns and Biologic Features of p53 Mutation Types in Korean Breast Cancer Patients.

PMID 27458004 2016 Targeted sequencing of refractory myeloma reveals a high incidence of mutations in CRBN and Ras pathway genes.

PMID 21343334 2011 Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

PMID 27730344 2017 Expression of circulating miRNAs associated with lymphocyte differentiation and activation in CLL-another piece in the puzzle.

PMID 9472631 1998 Effects of p53 mutants derived from lung carcinomas on the p53-responsive element (p53RE) of the MDM2 gene.

PMID 27149858 2016 Lenalidomide normalizes tumor vessels in colorectal cancer improving chemotherapy activity.

PMID 7732013 1995 A simple p53 functional assay for screening cell lines, blood, and tumors.

rs1057519747 in TP53 gene and Serous cystadenocarcinoma ovary PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Small cell carcinoma of lung PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519747 in TP53 gene and Squamous cell carcinoma of the head and neck PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.