Variant: rs1057519753 

    present in Gene: JAK1
    present in Chromosome: 1
    Position on Chromosome: 64846664
    Alleles of this Variant: C/A

rs1057519753 in JAK1 gene and Acute lymphoblastic leukemia with lymphomatous features PMID 19470474 2009 JAK mutations in high-risk childhood acute lymphoblastic leukemia.

PMID 19139102 2009 Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.

PMID 21680795 2011 Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

PMID 19838194 2009 Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia.

rs1057519753 in JAK1 gene and Leukemia, Acute, X-Linked PMID 19139102 2009 Acute lymphoblastic leukemia-associated JAK1 mutants activate the Janus kinase/STAT pathway via interleukin-9 receptor alpha homodimers.

rs1057519753 in JAK1 gene and Leukemia, Myelocytic, Acute PMID 21436584 2011 Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression.

PMID 21680795 2011 Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group.

rs1057519753 in JAK1 gene and Polycythemia Vera PMID 16239216 2005 JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor.