Variant: rs1057519981 

    present in Gene: TP53
    present in Chromosome: 17
    Position on Chromosome: 7674251
    Alleles of this Variant: A/C;G;T

rs1057519981 in TP53 gene and Adenocarcinoma of lung (disorder) PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Adenocarcinoma of pancreas PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Brain Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Chronic Lymphocytic Leukemia PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Colorectal Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Esophageal carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Gastric Adenocarcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Glioblastoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Li-Fraumeni Syndrome PMID 1737852 1992 Hereditary and acquired p53 gene mutations in childhood acute lymphoblastic leukemia.

PMID 17392385 2007 American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography.

PMID 12826609 2003 Understanding the function-structure and function-mutation relationships of p53 tumor suppressor protein by high-resolution missense mutation analysis.

PMID 24493721 2014 American Society of Clinical Oncology Expert Statement: collection and use of a cancer family history for oncology providers.

PMID 1978757 1990 Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.

PMID 8825920 1995 An extended Li-Fraumeni kindred with gastric carcinoma and a codon 175 mutation in TP53.

PMID 9452042 1998 A germline missense mutation R337C in exon 10 of the human p53 gene.

PMID 10484981 1999 Hereditary TP53 codon 292 and somatic P16INK4A codon 94 mutations in a Li-Fraumeni syndrome family.

PMID 1933902 1991 A germ line mutation in exon 5 of the p53 gene in an extended cancer family.

PMID 1565144 1992 Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms.

PMID 7887414 1995 Germ-line p53 mutations in 15 families with Li-Fraumeni syndrome.

PMID 2259385 1991 Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome.

rs1057519981 in TP53 gene and Liver carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Malignant Uterine Corpus Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Mammary Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Multiple Myeloma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Neoplastic Syndromes, Hereditary PMID 17606709 2007 Transcriptional functionality of germ line p53 mutants influences cancer phenotype.

PMID 15925506 2005 Identification of five new families strengthens the link between childhood choroid plexus carcinoma and germline TP53 mutations.

PMID 11793474 2002 Integrating mutation data and structural analysis of the TP53 tumor-suppressor protein.

PMID 12406399 2002 [Description of a new TP53 gene germline mutation in a family with the Li-Fraumeni syndrome. Genetic counselling to healthy mutation carriers].

PMID 21343334 2011 Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes.

rs1057519981 in TP53 gene and Serous cystadenocarcinoma ovary PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Squamous cell carcinoma of the head and neck PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Transitional cell carcinoma of bladder PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Uterine Carcinosarcoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519981 in TP53 gene and Uterine Cervical Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.