present in Gene: ITGAX
present in Chromosome: 16
Position on Chromosome: 31357553
Alleles of this Variant: T/C
rs11574637 in
ITGAX gene and
IGA Glomerulonephritis
PMID 25305756 2014 Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens.
rs11574637 in
ITGAX gene and
Leukemia, Myelocytic, Acute
PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.
rs11574637 in
ITGAX gene and
Lupus Erythematosus, Systemic
PMID 18204098 2008 In addition, variants on chromosome 16p11.22, near the genes encoding integrin alpha M (ITGAM, or CD11b) and integrin alpha X (ITGAX), were associated with SLE in the combined sample (rs11574637; odds ratio, 1.33; P=3x10(-11)).