Variant: rs118203998 

    present in Gene: PALB2
    present in Chromosome: 16
    Position on Chromosome: 23603471
    Alleles of this Variant: G/C;T

rs118203998 in PALB2 gene and Hereditary Breast and Ovarian Cancer Syndrome PMID 21365267 2011 PALB2 mutations in familial breast and pancreatic cancer.

PMID 26315354 2015 Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.

PMID 19609323 2009 Structural basis for recruitment of BRCA2 by PALB2.

PMID 17200671 2007 Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.

rs118203998 in PALB2 gene and Malignant neoplasm of breast PMID 20927582 2011 Mutations in BRCA2 and PALB2 in male breast cancer cases from the United States.

PMID 19584259 2009 PALB2 functionally connects the breast cancer susceptibility proteins BRCA1 and BRCA2.

PMID 19609323 2009 Structural basis for recruitment of BRCA2 by PALB2.

PMID 17200668 2007 PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.

PMID 25099575 2014 Breast-cancer risk in families with mutations in PALB2.

PMID 17200671 2007 Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.

PMID 26296701 2015 Exome sequencing reveals frequent deleterious germline variants in cancer susceptibility genes in women with invasive breast cancer undergoing neoadjuvant chemotherapy.

PMID 26283626 2015 Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls.

PMID 26641009 2016 Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.

PMID 26315354 2015 Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.

PMID 21365267 2011 PALB2 mutations in familial breast and pancreatic cancer.

PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.

PMID 24728327 2014 Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

PMID 24949998 2014 Assessment of PALB2 as a candidate melanoma susceptibility gene.

PMID 24415441 2014 Comprehensive sequencing of PALB2 in patients with breast cancer suggests PALB2 mutations explain a subset of hereditary breast cancer.

rs118203998 in PALB2 gene and Neoplastic Syndromes, Hereditary PMID 17200671 2007 Biallelic mutations in PALB2 cause Fanconi anemia subtype FA-N and predispose to childhood cancer.

PMID 24728327 2014 Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

PMID 27356891 2016 Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes.

PMID 26845104 2016 Improving performance of multigene panels for genomic analysis of cancer predisposition.

PMID 28008555 2017 Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results.

PMID 26898890 2016 Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes in Patients Lacking Known BRCA Mutations.

PMID 21165770 2011 PALB2 mutations in German and Russian patients with bilateral breast cancer.

PMID 26681312 2016 Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.

PMID 22241545 2012 Rare germline mutations in PALB2 and breast cancer risk: a population-based study.

PMID 21365267 2011 PALB2 mutations in familial breast and pancreatic cancer.

PMID 17200668 2007 PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene.

PMID 26641009 2016 Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia.

PMID 26283626 2015 Prevalence of PALB2 mutations in Australian familial breast cancer cases and controls.