present in Gene: TNIP1
present in Chromosome: 5
Position on Chromosome: 151059427
Alleles of this Variant: C/G;T
rs1422673 in
TNIP1 gene and
Asthma
PMID 22694930 2012 Multiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67). rs1422673 was also associated with asthma in the published GABRIEL (P = .018) and EVE (P = 1.31 × 10(-5)) studies.
rs1422673 in
TNIP1 gene and
Myasthenia Gravis
PMID 23055271 2012 Risk for myasthenia gravis maps to a (151) Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08.