Variant: rs145518263

present in Gene: ADAM10 present in Chromosome: 15 Position on Chromosome: 58665141 Alleles of this Variant: T/C

rs145518263 in ADAM10 gene and ALZHEIMER DISEASE 18 PMID 24055016 2013 ADAM10 missense mutations potentiate β-amyloid accumulation by impairing prodomain chaperone function.

PMID 19608551 2009 Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity.