Variant: rs146460077 

    present in Gene: LOC107984111;WNT10A
    present in Chromosome: 2
    Position on Chromosome: 218882255
    Alleles of this Variant: C/T

rs146460077 in LOC107984111;WNT10A gene and TOOTH AGENESIS, SELECTIVE, 4 (disorder) PMID 27657131 2016 Eight Mutations of Three Genes (EDA, EDAR, and WNT10A) Identified in Seven Hypohidrotic Ectodermal Dysplasia Patients.

PMID 22581971 2012 Mutations in WNT10A are present in more than half of isolated hypodontia cases.

PMID 29178643 2017 Role of WNT10A in failure of tooth development in humans and zebrafish.

PMID 24311251 2014 WNT10A mutations also associated with agenesis of the maxillary permanent canines, a separate entity.

PMID 23401279 2013 Mutations in WNT10A are frequently involved in oligodontia associated with minor signs of ectodermal dysplasia.

PMID 21484994 2011 WNT10A and isolated hypodontia.

PMID 20979233 2011 Only four genes (EDA1, EDAR, EDARADD, and WNT10A) account for 90% of hypohidrotic/anhidrotic ectodermal dysplasia cases.

PMID 24449199 2014 WNT10A mutations account for ¼ of population-based isolated oligodontia and show phenotypic correlations.