Variant: rs17065417

present in Gene: LIN28B present in Chromosome: 6 Position on Chromosome: 104958399 Alleles of this Variant: A/C

rs17065417 in LIN28B gene and Neuroblastoma PMID 28545128 2017 Common variants upstream of MLF1 at 3q25 and within CPZ at 4p16 associated with neuroblastoma.

PMID 22941191 2012 Expression of LIN28B and let-7 miRNA correlated with rs17065417 genotype in neuroblastoma cell lines, and we observed significant growth inhibition upon depletion of LIN28B, specifically in neuroblastoma cells that were homozygous for the risk allele.