Variant: rs17109512 

    present in Gene: LOC105378449
    present in Chromosome: 10
    Position on Chromosome: 98367794
    Alleles of this Variant: G/A

rs17109512 in LOC105378449 gene and Aspartate aminotransferase measurement PMID 21900944 2011 We carried out a genome-wide association study of serum aspartate aminotransferase (AST) activity in 866 Amish participants of the Heredity and Phenotype Intervention Heart Study and identified significant association of AST activity with a cluster of single nucleotide polymorphisms located on chromosome 10q24.1 (peak association was rs17109512; P=2.80E-14), in the vicinity of GOT1, the gene encoding cytosolic AST (cAST).

rs17109512 in LOC105378449 gene and Leukemia, Myelocytic, Acute PMID 27903959 2017 Genome-wide haplotype association study identify the FGFR2 gene as a risk gene for acute myeloid leukemia.