Variant: rs28456

present in Gene: FADS1;FADS2 present in Chromosome: 11 Position on Chromosome: 61822009 Alleles of this Variant: A/C;G

rs28456 in FADS1;FADS2 gene and Bipolar Disorder PMID 28115744 2018 In the present GWAS (Phase I/II), which included 2964 BD and 61 887 control subjects from the Japanese population, we detected a novel susceptibility locus at 11q12.2 (rs28456, P=6.4 × 10<sup>-9</sup>), a region known to contain regulatory genes for plasma lipid levels (FADS1/2/3).

rs28456 in FADS1;FADS2 gene and Chronic Kidney Diseases PMID 29545352 2018 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.

rs28456 in FADS1;FADS2 gene and Kidney Failure, Chronic PMID 29545352 2018 Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms.

rs28456 in FADS1;FADS2 gene and Phosphatidylcholine measurement PMID 31551469 2019 Genetic architecture of human plasma lipidome and its link to cardiovascular disease.

rs28456 in FADS1;FADS2 gene and Phosphatidylinositol measurement PMID 31551469 2019 Genetic architecture of human plasma lipidome and its link to cardiovascular disease.