Variant: rs3815148 

    present in Gene: COG5
    present in Chromosome: 7
    Position on Chromosome: 107297975
    Alleles of this Variant: A/C

rs3815148 in COG5 gene and Degenerative polyarthritis PMID 20112360 2010 The C allele of rs3815148 on chromosome 7q22 (minor allele frequency 23%; intron 12 of the COG5 gene) was associated with a 1.14-fold increased risk (95% confidence interval 1.09-1.19) of knee and/or hand OA (P = 8 x 10(-8)) and also with a 30% increased risk of knee OA progression (95% confidence interval 1.03-1.64) (P = 0.03).