present in Gene: NOX4
present in Chromosome: 11
Position on Chromosome: 89363589
Alleles of this Variant: T/C
rs3913535 in
NOX4 gene and
Diabetes Mellitus, Non-Insulin-Dependent
PMID 30178632 2018 A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.
rs3913535 in
NOX4 gene and
Diabetic Retinopathy
PMID 30178632 2018 In the meta-analysis using multiple Caucasian cohorts (excluding GoDARTS), rs10765219 and rs11018670 showed associations for diabetic retinopathy (p = 0.003 and 0.007, respectively), while the p value of rs3913535 was not significant (p = 0.429).