present in Gene: GRHL3
present in Chromosome: 1
Position on Chromosome: 24342967
Alleles of this Variant: C/T
rs41268753 in
GRHL3 gene and
Cleft Palate
PMID 27018472 2016 In both the discovery and replication samples, rs41268753 conferred increased risk for CP (OR = 8.3, 95% CI 4.1-16.8; OR = 2.16, 95% CI 1.43-3.27, respectively).
PMID 28054174 2017 Genome-wide meta-analyses of nonsyndromic orofacial clefts identify novel associations between FOXE1 and all orofacial clefts, and TP63 and cleft lip with or without cleft palate.