Variant: rs4430796 

    present in Gene: HNF1B
    present in Chromosome: 17
    Position on Chromosome: 37738049
    Alleles of this Variant: A/G

rs4430796 in HNF1B gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 24509480 2014 Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

PMID 22961080 2013 A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans.

PMID 28869590 2017 Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.

PMID 22325160 2012 Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.

rs4430796 in HNF1B gene and Endometrial Carcinoma PMID 21499250 2011 We identified an endometrial cancer susceptibility locus close to HNF1B at 17q12 (rs4430796, P = 7.1 × 10(-10)) that is also associated with risk of prostate cancer and is inversely associated with risk of type 2 diabetes.

rs4430796 in HNF1B gene and Endometrial Neoplasms PMID 21499250 2011 Genome-wide association study identifies a common variant associated with risk of endometrial cancer.

rs4430796 in HNF1B gene and Malignant neoplasm of prostate PMID 18264096 2008 Multiple loci identified in a genome-wide association study of prostate cancer.

PMID 18264097 2008 Multiple newly identified loci associated with prostate cancer susceptibility.

rs4430796 in HNF1B gene and Nasopharyngeal carcinoma PMID 20512145 2010 A genome-wide association study of nasopharyngeal carcinoma identifies three new susceptibility loci.

rs4430796 in HNF1B gene and Prostate carcinoma PMID 17603485 2007 Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.

PMID 29892016 2018 Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci.

PMID 31562322 2019 12 new susceptibility loci for prostate cancer identified by genome-wide association study in Japanese population.

PMID 26443449 2015 Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer.

PMID 18264096 2008 Multiple loci identified in a genome-wide association study of prostate cancer.

rs4430796 in HNF1B gene and Prostate specific antigen measurement PMID 21160077 2010 Overall, we detected a genome-wide significant association between PSA levels and single-nucleotide polymorphisms (SNPs) at six loci: 5p15.33 (rs2736098), 10q11 (rs10993994), 10q26 (rs10788160), 12q24 (rs11067228), 17q12 (rs4430796), and 19q13.33 [rs17632542 (KLK3: I179T)], each with P(combined) <3 × 10(-10).