Variant: rs61816761 

    present in Gene: FLG;FLG-AS1
    present in Chromosome: 1
    Position on Chromosome: 152313385
    Alleles of this Variant: G/A;T

rs61816761 in FLG;FLG-AS1 gene and Allergic Reaction PMID 29083406 2017 Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

rs61816761 in FLG;FLG-AS1 gene and Arthralgia PMID 17030239 2006 Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

PMID 16444271 2006 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

PMID 16815158 2006 Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.

PMID 16550169 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.

rs61816761 in FLG;FLG-AS1 gene and Asthma PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs61816761 in FLG;FLG-AS1 gene and Childhood asthma PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs61816761 in FLG;FLG-AS1 gene and Dermatitis, Atopic PMID 17030239 2006 Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

PMID 16550169 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.

PMID 16444271 2006 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

PMID 16815158 2006 We evaluated the association of the loss-of-function mutations R501X and 2282del4 within the FLG gene in a large collection of 476 well-characterized white German families with AD by using the transmission-disequilibrium test.

rs61816761 in FLG;FLG-AS1 gene and Eczema PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs61816761 in FLG;FLG-AS1 gene and Erythema PMID 16444271 2006 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

PMID 17030239 2006 Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

PMID 16550169 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.

PMID 16815158 2006 Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.

rs61816761 in FLG;FLG-AS1 gene and Ichthyosis Vulgaris PMID 16550169 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.

PMID 23947670 2013 Filaggrin compound heterozygous patients carry mutations in trans position.

PMID 17030239 2006 Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

PMID 22403702 2012 Interplay of filaggrin loss-of-function variants, allergic sensitization, and eczema in a longitudinal study covering infancy to 18 years of age.

PMID 19874431 2010 Analysis of four prevalent filaggrin mutations (R501X, 2282del4, R2447X and S3247X) in Austrian and German patients with atopic dermatitis.

PMID 19839980 2009 Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure.

PMID 19501237 2009 Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease.

PMID 16815158 2006 Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.

PMID 18325573 2008 The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study.

PMID 16444271 2006 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

PMID 21514438 2011 Filaggrin genotype in ichthyosis vulgaris predicts abnormalities in epidermal structure and function.

rs61816761 in FLG;FLG-AS1 gene and Inflammatory dermatosis PMID 17030239 2006 Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

PMID 16550169 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.

PMID 16815158 2006 Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.

PMID 16444271 2006 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

rs61816761 in FLG;FLG-AS1 gene and Respiratory Tract Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.