Condition: Arthralgia
rs61816761 in
FLG;FLG-AS1 gene and
Arthralgia
PMID 17030239 2006 Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.
PMID 16444271 2006 Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.
PMID 16815158 2006 Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.
PMID 16550169 2006 Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.
rs151344517 in
LOC107985154;AFG3L2;TUBB6 gene and
Arthralgia
PMID 20725928 2010 Missense mutations in the AFG3L2 proteolytic domain account for ∼1.5% of European autosomal dominant cerebellar ataxias.