Condition: Aortic valve calcification
rs6702619 in
LINC01708 gene and
Aortic valve calcification
PMID 29511167 2018 A transcriptome-wide association study identifies PALMD as a susceptibility gene for calcific aortic valve stenosis.
rs10455872 in
LPA gene and
Aortic valve calcification
PMID 23388002 2013 One SNP in the lipoprotein(a) (LPA) locus (rs10455872) reached genomewide significance for the presence of aortic-valve calcification (odds ratio per allele, 2.05; P=9.0×10(-10)), a finding that was replicated in additional white European, African-American, and Hispanic-American cohorts (P<0.05 for all comparisons).