PMID 22281684 2012 To investigate the cause of the limited therapeutic effect of PLX4032 in BRAF(V600E) mutant colon tumours, here we performed an RNA-interference-based genetic screen in human cells to search for kinases whose knockdown synergizes with BRAF(V600E) inhibition.
rs1057519803 in
ERBB3 gene and
Colonic Neoplasms
PMID 23680147 2013 Oncogenic ERBB3 mutations in human cancers.
rs56848936 in
SYMPK gene and
Colonic Neoplasms
PMID 28295283 2017 Novel colon cancer susceptibility variants identified from a genome-wide association study in African Americans.