Condition: Glioblastoma Multiforme
rs55705857 in
CCDC26 gene and
Glioblastoma Multiforme
PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
PMID 30152087 2018 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
rs145929329 in
CDKN2B-AS1 gene and
Glioblastoma Multiforme
PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.
PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
PMID 30152087 2018 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
rs11979158 in
EGFR gene and
Glioblastoma Multiforme
PMID 30152087 2018 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.
PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
rs10852606 in
HEATR3 gene and
Glioblastoma Multiforme
PMID 28346443 2017 We identified five new loci for glioblastoma (GBM) at 1p31.3 (rs12752552; P = 2.04 × 10<sup>-9</sup>, odds ratio (OR) = 1.22), 11q14.1 (rs11233250; P = 9.95 × 10<sup>-10</sup>, OR = 1.24), 16p13.3 (rs2562152; P = 1.93 × 10<sup>-8</sup>, OR = 1.21), 16q12.1 (rs10852606; P = 1.29 × 10<sup>-11</sup>, OR = 1.18) and 22q13.1 (rs2235573; P = 1.76 × 10<sup>-10</sup>, OR = 1.15), as well as eight loci for non-GBM tumors at 1q32.1 (rs4252707; P = 3.34 × 10<sup>-9</sup>, OR = 1.19), 1q44 (rs12076373; P = 2.63 × 10<sup>-10</sup>, OR = 1.23), 2q33.3 (rs7572263; P = 2.18 × 10<sup>-10</sup>, OR = 1.20), 3p14.1 (rs11706832; P = 7.66 × 10<sup>-9</sup>, OR = 1.15), 10q24.33 (rs11598018; P = 3.39 × 10<sup>-8</sup>, OR = 1.14), 11q21 (rs7107785; P = 3.87 × 10<sup>-10</sup>, OR = 1.16), 14q12 (rs10131032; P = 5.07 × 10<sup>-11</sup>, OR = 1.33) and 16p13.3 (rs3751667; P = 2.61 × 10<sup>-9</sup>, OR = 1.18).
rs11233250 in
MIR4300HG gene and
Glioblastoma Multiforme
PMID 28346443 2017 We identified five new loci for glioblastoma (GBM) at 1p31.3 (rs12752552; P = 2.04 × 10<sup>-9</sup>, odds ratio (OR) = 1.22), 11q14.1 (rs11233250; P = 9.95 × 10<sup>-10</sup>, OR = 1.24), 16p13.3 (rs2562152; P = 1.93 × 10<sup>-8</sup>, OR = 1.21), 16q12.1 (rs10852606; P = 1.29 × 10<sup>-11</sup>, OR = 1.18) and 22q13.1 (rs2235573; P = 1.76 × 10<sup>-10</sup>, OR = 1.15), as well as eight loci for non-GBM tumors at 1q32.1 (rs4252707; P = 3.34 × 10<sup>-9</sup>, OR = 1.19), 1q44 (rs12076373; P = 2.63 × 10<sup>-10</sup>, OR = 1.23), 2q33.3 (rs7572263; P = 2.18 × 10<sup>-10</sup>, OR = 1.20), 3p14.1 (rs11706832; P = 7.66 × 10<sup>-9</sup>, OR = 1.15), 10q24.33 (rs11598018; P = 3.39 × 10<sup>-8</sup>, OR = 1.14), 11q21 (rs7107785; P = 3.87 × 10<sup>-10</sup>, OR = 1.16), 14q12 (rs10131032; P = 5.07 × 10<sup>-11</sup>, OR = 1.33) and 16p13.3 (rs3751667; P = 2.61 × 10<sup>-9</sup>, OR = 1.18).
rs3851634 in
POLR3B gene and
Glioblastoma Multiforme
PMID 26424050 2015 After genotyping an additional 1,490 cases and 1,723 controls we identify new risk loci for glioblastoma (GBM) at 12q23.33 (rs3851634, near POLR3B, P=3.02 × 10(-9)) and non-GBM at 10q25.2 (rs11196067, near VTI1A, P=4.32 × 10(-8)), 11q23.2 (rs648044, near ZBTB16, P=6.26 × 10(-11)), 12q21.2 (rs12230172, P=7.53 × 10(-11)) and 15q24.2 (rs1801591, near ETFA, P=5.71 × 10(-9)).
rs12752552 in
RAVER2 gene and
Glioblastoma Multiforme
PMID 28346443 2017 We identified five new loci for glioblastoma (GBM) at 1p31.3 (rs12752552; P = 2.04 × 10<sup>-9</sup>, odds ratio (OR) = 1.22), 11q14.1 (rs11233250; P = 9.95 × 10<sup>-10</sup>, OR = 1.24), 16p13.3 (rs2562152; P = 1.93 × 10<sup>-8</sup>, OR = 1.21), 16q12.1 (rs10852606; P = 1.29 × 10<sup>-11</sup>, OR = 1.18) and 22q13.1 (rs2235573; P = 1.76 × 10<sup>-10</sup>, OR = 1.15), as well as eight loci for non-GBM tumors at 1q32.1 (rs4252707; P = 3.34 × 10<sup>-9</sup>, OR = 1.19), 1q44 (rs12076373; P = 2.63 × 10<sup>-10</sup>, OR = 1.23), 2q33.3 (rs7572263; P = 2.18 × 10<sup>-10</sup>, OR = 1.20), 3p14.1 (rs11706832; P = 7.66 × 10<sup>-9</sup>, OR = 1.15), 10q24.33 (rs11598018; P = 3.39 × 10<sup>-8</sup>, OR = 1.14), 11q21 (rs7107785; P = 3.87 × 10<sup>-10</sup>, OR = 1.16), 14q12 (rs10131032; P = 5.07 × 10<sup>-11</sup>, OR = 1.33) and 16p13.3 (rs3751667; P = 2.61 × 10<sup>-9</sup>, OR = 1.18).
rs2562152 in
RHBDF1 gene and
Glioblastoma Multiforme
PMID 28346443 2017 We identified five new loci for glioblastoma (GBM) at 1p31.3 (rs12752552; P = 2.04 × 10<sup>-9</sup>, odds ratio (OR) = 1.22), 11q14.1 (rs11233250; P = 9.95 × 10<sup>-10</sup>, OR = 1.24), 16p13.3 (rs2562152; P = 1.93 × 10<sup>-8</sup>, OR = 1.21), 16q12.1 (rs10852606; P = 1.29 × 10<sup>-11</sup>, OR = 1.18) and 22q13.1 (rs2235573; P = 1.76 × 10<sup>-10</sup>, OR = 1.15), as well as eight loci for non-GBM tumors at 1q32.1 (rs4252707; P = 3.34 × 10<sup>-9</sup>, OR = 1.19), 1q44 (rs12076373; P = 2.63 × 10<sup>-10</sup>, OR = 1.23), 2q33.3 (rs7572263; P = 2.18 × 10<sup>-10</sup>, OR = 1.20), 3p14.1 (rs11706832; P = 7.66 × 10<sup>-9</sup>, OR = 1.15), 10q24.33 (rs11598018; P = 3.39 × 10<sup>-8</sup>, OR = 1.14), 11q21 (rs7107785; P = 3.87 × 10<sup>-10</sup>, OR = 1.16), 14q12 (rs10131032; P = 5.07 × 10<sup>-11</sup>, OR = 1.33) and 16p13.3 (rs3751667; P = 2.61 × 10<sup>-9</sup>, OR = 1.18).
rs2297440 in
RTEL1;RTEL1-TNFRSF6B gene and
Glioblastoma Multiforme
PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
PMID 30152087 2018 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.
rs2235573 in
SLC16A8 gene and
Glioblastoma Multiforme
PMID 28346443 2017 We identified five new loci for glioblastoma (GBM) at 1p31.3 (rs12752552; P = 2.04 × 10<sup>-9</sup>, odds ratio (OR) = 1.22), 11q14.1 (rs11233250; P = 9.95 × 10<sup>-10</sup>, OR = 1.24), 16p13.3 (rs2562152; P = 1.93 × 10<sup>-8</sup>, OR = 1.21), 16q12.1 (rs10852606; P = 1.29 × 10<sup>-11</sup>, OR = 1.18) and 22q13.1 (rs2235573; P = 1.76 × 10<sup>-10</sup>, OR = 1.15), as well as eight loci for non-GBM tumors at 1q32.1 (rs4252707; P = 3.34 × 10<sup>-9</sup>, OR = 1.19), 1q44 (rs12076373; P = 2.63 × 10<sup>-10</sup>, OR = 1.23), 2q33.3 (rs7572263; P = 2.18 × 10<sup>-10</sup>, OR = 1.20), 3p14.1 (rs11706832; P = 7.66 × 10<sup>-9</sup>, OR = 1.15), 10q24.33 (rs11598018; P = 3.39 × 10<sup>-8</sup>, OR = 1.14), 11q21 (rs7107785; P = 3.87 × 10<sup>-10</sup>, OR = 1.16), 14q12 (rs10131032; P = 5.07 × 10<sup>-11</sup>, OR = 1.33) and 16p13.3 (rs3751667; P = 2.61 × 10<sup>-9</sup>, OR = 1.18).
rs7732320 in
SSBP2 gene and
Glioblastoma Multiforme
PMID 22472174 2012 SSBP2 variants are associated with survival in glioblastoma patients.
rs10069690 in
TERT gene and
Glioblastoma Multiforme
PMID 30152087 2018 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.
PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.
rs35850753 in
TP53 gene and
Glioblastoma Multiforme
PMID 26424050 2015 Genome-wide association study identifies multiple susceptibility loci for glioma.
PMID 30152087 2018 Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.
PMID 28346443 2017 Genome-wide association study of glioma subtypes identifies specific differences in genetic susceptibility to glioblastoma and non-glioblastoma tumors.