Gene: SSBP2

Alternate names for this Gene: HSPC116|SOSS-B2

Gene Summary: This gene encodes a subunit of a protein complex that interacts with single-stranded DNA and is involved in the DNA damage response and maintenance of genome stability. The encoded protein may also play a role in telomere repair. A variant of this gene may be associated with survival in human glioblastoma patients.

Gene is located in Chromosome: 5

Location in Chromosome : 5q14.1

Description of this Gene: single stranded DNA binding protein 2

Type of Gene: protein-coding

rs446064 in SSBP2 gene and Adolescent idiopathic scoliosis PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.

rs10035291 in SSBP2 gene and Bipolar Disorder PMID 31043756 2019 Genome-wide association study identifies 30 loci associated with bipolar disorder.

rs411840 in SSBP2 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs10942267 in SSBP2 gene and Body mass index PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.

PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7732320 in SSBP2 gene and Glioblastoma PMID 22472174 2012 SSBP2 variants are associated with survival in glioblastoma patients.

rs7732320 in SSBP2 gene and Glioblastoma Multiforme PMID 22472174 2012 SSBP2 variants are associated with survival in glioblastoma patients.

rs446064 in SSBP2 gene and SCOLIOSIS, ISOLATED, SUSCEPTIBILITY TO, 3 PMID 30019117 2018 The coexistence of copy number variations (CNVs) and single nucleotide polymorphisms (SNPs) at a locus can result in distorted calculations of the significance in associating SNPs to disease.